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Olivia I. Okereke, MD, SM

Instructor in Psychiatry
Harvard Medical School

Associate Epidemiologist, Division of Aging
Associate Psychiatrist, Department of Psychiatry
Department of Medicine
Brigham and Women's Hospital

Research Interests

Dr. Okereke is a board-certified geriatric psychiatrist who is based at Brigham and Women’s Hospital (BWH). A graduate of Harvard College and Yale University School of Medicine, she completed a general psychiatry residency at the Massachusetts General Hospital (MGH)/ McLean Hospital program and, later, a fellowship in geriatric psychiatry at McLean. In addition to her clinical training, Dr. Okereke completed a Master of Science in Epidemiology degree at the Harvard School of Public Health. She is currently an Instructor in Psychiatry at Harvard Medical School.

Most of Dr. Okereke’s time is devoted to an NIH-funded multi-year grant to evaluate the relationship between metabolic and lifestyle risk factors (such as diabetes, insulin levels, exercise, and physical activity) and cognitive function in older participants of two major BWH/Harvard cohorts – the Nurses’ Health Study I and the Physicians’ Health Study II. Publications of this work have appeared in such journals as Archives of Internal Medicine, the Journal of Clinical Endocrinology and Metabolism and Neurobiology of Aging. In addition, she maintains a clinical appointment as an affiliate staff psychiatrist at MGH in the Gerontology Research Unit and also sees patients in the neuropsychiatry clinical practice in the BWH Division of Cognitive and Behavioral Neurology, where her work is focused primarily on assessment and treatment of psychopathology in geriatric patients, particularly those with memory disorders.

Selected Publications

van Dyck CH, Gelernter JE, MacAvoy MG, Avery RA, Criden M, Okereke O, Varma P, Seibyl JP, Hoffer PB. Absence of an apolipoprotein E epsilon4 allele is associated with increased parietal regional cerebral blood flow asymmetry in Alzheimer disease. Arch Neurol. 1998 Nov;55(11):1460-6. [abstract]

Okereke OI, Folsom DP. Medical comorbidity in geriatric psychiatry. Am J Geriatr Psychiatry. 2005 Mar;13(3):177-9. No abstract available.

Okereke OI, Hankinson SE, Hu FB, Grodstein F. Plasma C peptide level and cognitive function among older women without diabetes mellitus. Arch Intern Med. 2005 Jul 25;165(14):1651-6. [abstract]

Okereke OI, Kang JH, Ma J, Hankinson SE, Pollak MN, Grodstein F. Plasma IGF-I levels and cognitive performance in older women. Neurobiol Aging. 2007 Jan;28(1):135-42. Epub 2005 Dec 7. [abstract]

Okereke OI, Kang JH, Ma J, Gaziano JM, Grodstein F. Midlife plasma insulin-like growth factor I and cognitive function in older men. J Clin Endocrinol Metab. 2006 Nov;91(11):4306-12. Epub 2006 Aug 15. [abstract]

Okereke OI, Kang JH, Gaziano JM, Ma J, Stampfer MJ, Grodstein F. Plasma C-Peptide and Cognitive Performance in Older Men Without Diabetes. Am J Geriatr Psychiatry. 2006 Dec;14(12):1041-1050. [abstract]