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CHANNING LABORATORY NEWS
Editor's Note: Please take a moment to read the article A Brief History of the Channing Laboratory written by Amalie M. Kass in the "History" section of our site. It was on May 1, 1857, 150 years ago, the first patients were accepted to the Channing Street Home for Sick and Destitute Women and the story Ms. Kass tells about our beginning is truly remarkable. Although the Channing Lab of today was not a legal entity until much later and serves a vastly different purpose today, we like to think that the next 150 years will bring even more discovery and growth than our first 150.
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CONGRATULATIONS!!
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CONGRATULATIONS!!
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IN GRATEFUL APPRECIATION
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CONGRATULATIONS!!
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ANNOUNCEMENTS
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NEWS
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Dr. Walter Willett answers questions on the newest nutrition report, Second Expert Report on Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective released in November, 2007.
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Former Channing Laboratory scientist receives substantial research award.
The National Institute of Allergy and Infectious Diseases awarded Daniel Kuritzkes, HMS professor of medicine at Brigham and Women's Hospital, a MERIT award in the amount of $2.7 million over five years, with the possibility of an extension for another five years. Kuritzkes will use the award for research on the development of resistance to antiretroviral drugs.
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Channing Laboratory researchers publish new study findings on flavonoid-rich diets and ovarian cancer.
In findings published in the International Journal of Cancer November 15, 2007 issue, research from the Channing Lab and lead author Dr. Margaret Gates found that frequent consumption of foods containing the flavonoid Kaempferol, including herbal tea and broccoli, was associated with a reduced risk of ovarian cancer. The researchers also found a decreased risk in women who consumed large amounts of the flavonoid luteolin, which is found in foods such as carrots, peppers, and cabbage. Using data from over 66,000 women enrolled in the Nurse's Health Study, Gates and colleagues calculated intake of the flavonoids myricetin, kaempferol, quercetin, luteolin, and apigenin and found a 40 percent reduction in ovarian cancer risk amount the women with the highest kaempferol intake. "This is good news because there are few lifestyle factors known to reduce a woman's risk of ovarian cancer," said Dr. Gates. "Although additional research is needed, these findings suggest that consuming a diet rich in flavonoids may be protective."
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Dr. Francine Grodstein, respected Channning Laboratory researcher, publishes important new study on cognitive decline in men. In the November 12th issue of Archives of Internal Medicine, Dr. Grodstein and colleagues at BWH published evidence that men taking beta-carotine supplements for more than 15 years or longer may have less cognitve decline and better verbal memory than those who are not using these supplements. The study utilized data from two groups enrolled in the Physician's Health Study II enrolled between 1982 and 2002. "Our research supports the possibility of successful interventions at early stages of brain aging in healthy adults," concluded Grodstein. "And there's no reason to believe that beta-carotene supplementation does not carry the same benefit for women as it does men, though this has yet to be tested.
Dr. Grodstein also shared her views with the Washington Post, Reuters, and the US News and World Report on their online publication sites.
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Channing associate scientist, Dr. Joann Manson, receives cardio award. The North American Menopause Society presented the 2007 Postmenopausal Cardiovascular Research Award to Joann Manson, the Elizabeth F. Brigham professor of women's health at HMS and Brigham and Women's Hospital, at the society's annual scientific sessions in Dallas last month. The award honors an individual whose research has advanced the understanding of cardiovascular health in women beyond menopause.
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Dr. Walter Willett recognized as AAAS fellow.
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NIH awards multi-million dollar grant to study kidney stones.
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Noted Channing Laboratory scientist is awarded multi-million dollar grant from NHLBI. Dr. Edwin Silverman is Co-Principal Investigator with colleagues from the National Jewish Medical and Research Center in a comprehensive new study on COPD and its genetic, epidemiological, and radiological characteristics. Over 30 million dollars will be devoted to the study which will enroll over 10,000 participants, a third of which will be African American. The African American segment represents a group showing a rapid increase of the disease without any real understanding of the reasons for the sudden increase. The Harvard School of Public Health, Johns Hopkins University, and the University of Colorado will also be providing input to the study. This study is truly important as COPD is the fourth leading cause of death in the U.S. and increasing in frequency. Click HERE to read the Harvard Focus article.
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Channing Associate Scientist publishes ground-breaking new book. Arnold S. Relman, professor emeritus at Harvard Medical School and former editor-in-chief of the New England Journal of Medicine has been a familiar fixture here at the Channing for many years. We are proud to have assisted Dr. Relman in publishing his newest book, "A Second Opinion: Rescuing America's Healthcare". Dr. Relman recently held an enormously successful book signing at the Harvard Coop, Harvard Square, on September 24, 2007. Copies are still available for those who have missed it so don't hesitate to pick one up to add to your library of important and relevant publications.
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Dr. Lorelei Mucci, BWH and HSPH scientist, assesses link of acrylamide and breast cancer.
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Channing scientist comments on trans fat in consumer products
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Channing researcher and colleagues receive worldwide coverage in new study. Eunyoung Cho, Sc.D. and Channing Laboratory scientists, using data from women enrolled in the Nurses' Health Study found the opposite of what they were looking for when they discoverd that choline may actually be encouraging the growth of polyps rather than having the protective affect previously believed.
Click HERE to read this important new Press Release by BWH.
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New breast cancer study has surprising results.
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Channing scientist offers an explanation for why over 80 percent of CF patients develop this chronic lung infection.
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CONGRATULATIONS!!!
BWH Bulletin, June 15, 2007
5 YEAR SERVICE AWARDS
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Dr. Ichiro Kawachi co-edits new book of health globalization
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Noted Channing scientist identifies new breast cancer gene variant. * * *
BWH researchers and Channing scientist release results of folate and pancreatic cancer risk study. Eva Schernhammer, MD, DrPH and BWH colleagues, studying whether nutrients nutrients such as folate, vitamin B6, and vitamin B12, found no significant assocation between these nutrient levels and a reduced risk for pancreatic cancer but also found, as an exception that thinner people intaking folate through diet appear to have some protection against the disease. Click HERE to read the BWH Press Release.
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Channing scientist publishes a study showing no benefit in low-dose aspirin and cognitive decline in women. Jae Hee Kang, Sc.D. and colleagues from BWH, using data from the Women's Health Study, observed no benefit of low-dose aspirin in slowing cognitive decline in generally healthy women aged 65 years or more. This study appeared on the British Medical Journal's website. Click HERE to read the BWH Press Release on this surprising study.
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Harvard study: No risk of cancer from abortion * * *
Channing scientist participates in 2007 Postgraduate Nutrition Symposium.
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Asthma and Domestic Abuse? New study links domestic abuse and the risk of developing asthma. Dr. Rosalind Wright, well known respiratory researcher here at the Channing, Dr. S. V. Subramanian, and colleagues studied data from over 90,000 households in the Indian National Family Health Survey dating from 1998 to 1999 with a focus on asthma risks. Their study showed there was definitely a link between greater asthma risk and domestic violence. Even more telling is the finding that other family members were at greater risk of developing asthma, one of the fastest growing health problems in recent years. Click HERE to read more about this informative study.
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Channing scientists help publish results from long-running study on prostate cancer. Dr. Meir Stampfer, Dr. Jing Ma, and Dr. Haojie Li participated in an 18 year study of the relationship of Vitamin D and prostate cancer using data from the Physician's Health Study. This study is particularly important in that it uses a large amount of participants over a longer period of time, enabling the team to publish a more comprehensive study and provide support to the theory vitamin D and the deadly prostate cancer are definitely linked. Click HERE to go to the Harvard Gazette and read more about this important new research.
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Channing researcher releases results of new study on over-the-counter pain relievers and high blood pressure in men. John P. Forman, M.D. and researchers from BWH, using data from the Health Professionals Follow-up Study, have found that acetamenophen, ibuprofen, and aspirin, increase the risk of developing high blood pressure in middle-aged men. These findings are published in the February 26 issue of the Archives of Internal Medicine. Click HERE to read more about the results of this important study.
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Former Channing scientist is first author of illuminating new study in disease prevention. Dr. Anushua Sinha, former Channing scientist and now assistant professor of preventive medicine and community health at the University of Medicine & Dentistry of New Jersey, is first author in a newly published study by colleague Tracy Lieu, senior author dealing with developing nations and the lack of preventive cost-effective medicine distribution. Dr. Sinha helped in the development of a computer model estimating how vaccination could possible affect a broad spectrum of developing nations. Click HERE to go to the Harvard Focus to read about this ground-breaking study.
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Channing scientist does presentation for Nursing Grand Rounds. Susan Hankinson, ScD, MPH, RN, principal investigator for the Nurses' Health Study, presents "The Nurses' Health Study: Finding Ways to Improve Women's Health," on Friday, March 2, at 11:30 a.m. in Carrie Hall as part of the Nursing Grand Rounds Visiting Scholar Program.
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BWH and Channing Laboratory receive philanthropic funds for cancer research and prevention. Mark Kostegan, Chief Development Officer for BWH, announced that BWH and the Channing Lab will receive funds from the Zukor family's "Conquer Cancer Coalition of Massachusetts" for research in cancer prevention. The funds were raised from sales of the Conquer Cancer license plate. We offer our sincerest thanks to the Zukor family for their help in fighting this most devastating disease. For more information, visit www.conquercancer.org
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Important new study on trans-fats unveiled by Channing Lab scientist and colleagues. For many couples wishing to start a family, infertility has been a major concern. Dr. Walter Willett, famed Channing Laboratory and HSPH expert on nutrition, and colleagues have published important new data dealing with the link between consumption of trans-fats and infertility. As the founding principal investigator of the Nurses' Health Study II, Dr. Willett and colleagues Jorge Charvarro and others collected data from over 18,000 women between the ages of 24 and 42. The findings indicated a strong link between infertility and trans-fat. Click HERE to read more in depth about this now famous problem in obesity.
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Dr. JoAnn Manson publishes new book on women's health. McGraw-Hill has just published Channing Laboratory associate scientist Dr. JoAnn Manson and colleague Shari Bassuk's newest book titled, " Hot Flashes, Hormones and Your Health: Breakthrough Findings to Help You Sail Through Menopause". Click HERE to read more about this important research guide to the safe use of hormone replacement therapy.
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Dr. Douglas Dockery, highly respected scientist with the Channing, pens an editorial on a new and important air pollution study.
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An association of circulating vitamin D and multiple sclerosis is outcome of new study by Channing Laboratory scientist. Dr. Alberto Ascherio and colleague Kassandra Munger have published the results of the first large-scale study of the association of vitamin D and MS. This important new study could lead to setting new parameters for using vitamin D to protect against this dreaded disease. Click HERE to go to the Harvard Focus web page to continue reading about this breakthrough study.
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Former Channing Laboratory scientist named to full Professorship. All of us here at the Channing Lab wish to extend our heartiest congratulations to Dr. Daniel Kuritzkes on the occasion of his appointment to Professor of Medicine, Brigham and Women's Hospital. As head of the Harvard AIDS Clinical Trials Group, he has made great strides in the investigation of new therapeutic research in the battle against AIDS. We wish him much success in his new position.
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The NIH has awarded over 8 million dollars to 
In a study of 100,000 women, 
