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Susan A. Korrick, MD

Assistant Professor of Medicine
Harvard Medical School

Associate Physician
Brigham and Women's Hospital

Research Interests

My current research activities are focused in three areas: 1) the developmental and reproductive toxicities of polychlorinated biphenyls (PCBs) and chlorinated pesticides; 2) chronic lead toxicities in middle-aged and elderly adults; and 3) the relationship of perimenopausal alterationsin bone metabolism with changes in kinetics, distribution, and toxicities of lead. I am the Project Director/Principal Investigator (PI) of a longitudinal study of the impact of low-level intrauterine exposures to PCBs, pesticides, and lead on fetal and infant development. This work included the development of sensitive biomarkers of intrauterine PCB and pesticide exposures in population-based cohorts. In related research, I am the PI of a pilot grant to study the relationship between PCBs and infertility among residents of a Russian community with extensive environmental PCB contamination. I am the co-PI and a co-investigator of two studies investigating the relationship of low-level lead exposures with aging-associated chronic diseases, including hypertension, renal insufficiency, and cognitive impairment. Our research group has refined noninvasive methods for assessment of bone lead concentration which is hypothesized to be an excellent biomarker of lead-associated chronic disease risk. In conjunction with this exposure assessment capability, I am developing several projects to study the relationship of lead to aging-associated changes in bone metabolism, declines in bone mineral density, and development of osteoporosis.

Selected Publications

Korrick SA, Rest KM, Davis LK, Christiani DC. Use of state workers' compensation data for occupational carpal tunnel syndrome surveillance: a feasability study in Massachusetts. Am J Ind Med. 1994 Jun;25(6):837-50. [abstract]

Hu H, Watanabe H, Payton M, Korrick S, Rotnitzky A. The relationship between bone lead and hemoglobin. JAMA. 1994 Nov 16;272(19):1512-7. [abstract]

Hu H, Aro A, Payton M, Korrick S, Sparrow D, Weiss ST, Rotnitzky A. The relationship of bone and blood lead to hypertension: the Normative Aging Study. JAMA. 1996 Apr 17;275(15):1171-6. Erratum in: JAMA 1996 Oct 2;276(13):1038. [abstract]

Hu H, Payton M, Korrick S, Aro A, Sparrow D, Weiss ST, Rotnitzky A. Determinants of bone and blood lead levels among community-exposed middle-aged to elderly men: the Normative Aging Study. Am J Epidemiol. 1996 Oct 15;144(8):749-59. [abstract]

Korrick SA, Neas LM, Dockery DW, Gold DR, Allen GA, Hill LB, Kimball KD, Rosner BA, Speizer FE. Effects of ozone and other pollutants on the pulmonary function of adult hikers. Environ Health Perspect. 1998 Feb;106(2):93-9. [abstract]

Korrick SA, Altshul L. High breast milk levels of polychlorinated biphenyls (PCBs) among four women living adjacent to a PCB-contaminated waste site. Environ Health Perspect. 1998 Aug;106(8):513-8. [abstract]

Korrick SA, Hunter DJ, Rotnitzky A, Hu H, Speizer FE. Lead and hypertension in a sample of middle-aged women. Am J Public Health. 1999 Mar;89(3):330-5. [abstract]

Feskanich D, Korrick SA, Greenspan SL, Rosen HN, Colditz GA. Moderate alcohol consumption and bone density among postmenopausal women. 1999 Jan-Feb;8(1):65-73. [abstract]