Michelle D. Holmes, MD Assistant Professor of Medicine Harvard Medical School Associate Physician Brigham and Women's Hospital   michelle.holmes@channing. harvard.edu

Research Interests My research interests include: dietary factors and breast cancer incidence; in particular dietary fat and types of fat. I am interested in how dietary factors and patterns can alter endogenous hormones as a mechanism for altering risk of hormone-dependent cancer. I am also interested in how diet and other lifestyle factors (physical activity, weight loss, social factors, etc.) can affect survival among those already diagnosed with breast cancer and prostate cancer.

Selected Publications Holmes MD, Chen WY, Reskanich D, Kroenke, CH, Colditz, GA. Physical activity and survival after breast cancer diagnosis. JAMA. 2005 May 25;293(20):2479-86. [abstract] Adebamowo CA, Spiegelman D, Danby FW, Frazier AL, Willett WC, Holmes MD. High school dietary dairy intake and teenage acne. J Am Acad Dermatol. 2005 Feb;52(2):207-14. [abstract] Kroenke CH, Chen WY, Rosner B, Holmes MD. Weight, weight gain, and survival after breast cancer diagnosis. J Clin Oncol. 2005 Mar 1;23(7):1370-8. Epub 2005 Jan 31. [abstract] Holmes MD, Willett WC. Does diet affect breast cancer risk? Breast Cancer Res. 2004;6(4):170-8. Epub 2004 Jun 17. Review. [abstract] Holmes MD, Liu S, Hankinson SE, Colditz GA. Dietary carbohydrates, fiber, and breast cancer risk. Am J Epidemiol. 2004 Apr 15;159(8):732-9. [abstract] Holmes MD, Stampfer MJ, Colditz GA, Rosner B, Hunter DJ, Willett WC. Dietary factors and the survival of women with breast carcinoma. Cancer. 1999 Sep 1;86(5):826-35. Erratum in: Cancer 1999 Dec 15;86(12):2707-8. [abstract] Holmes MD, Hunter DJ, Colditz GA, Stampfer MJ, Hankinson SE, Speizer FE, Rosner B, Willett WC. Association of dietary intake of fat and fatty acids with risk of breast cancer. JAMA. 1999 Mar 10;281(10):914-20. [abstract] Holmes MD, Hunter DJ, Hankinson SE. Very low fat diets and risk of breast cancer. Am J Epidemiol 1996;143:S59. Jones CP, Holmes MD, Wolf AM. Can behavioral risk factors explain the difference in body mass index between African American and European American nurses? Am J Epidemiol 1996;143:S16. Holmes MD, Willett WC. Can breast cancer be prevented by dietary and lifestyle changes? (editorial) Ann Med. 1995 Aug;27(4):429-30. No abstract available.