Associate Epidemiologist
Brigham and Women's Hospital

jiali.han@channing.harvard.edu

My research interests are breast and skin cancer genetic susceptibility and etiology, DNA repair and related molecular pathways, and ultraviolet exposures. I am interested in understanding the influence of genetic and environmental exposures in cancer etiology and prevention, particularly breast and skin cancer. I am currently engaged in working on inherited susceptibility, particularly focusing on DNA repair and related pathways. The skin cancer research includes melanoma, squamous cell carcinoma, and basal cell carcinoma. I continue to pursue my interest in genetic susceptibility to skin cancer examining additional candidate molecular pathways, such as cell cycle genes and pigmentation genes. In addition to genetic susceptibility research, I am also interested in understanding the role of ultraviolet exposures (artificial and natural) in disease etiology in various populations.

Han J, Hankinson SE, De Vivo I, Spiegelman D, Tamimi R, Mohrenweiser HW, Colditz GA, Hunter DJ. A prospective study of XRCC1 haplotypes and their interaction with plasma carotenoids on breast cancer risk. Cancer Res. 2003;63(23):8536-41. [abstract]

Han J, Hankinson SE, Zhang S, De Vivo I, Hunter DJ. Interaction between genetic variations in DNA repair genes and plasma folate on breast cancer risk. Cancer Epidemiol Biomarkers Prev. 2004;13:520-4. [abstract]

Han J, Colditz GA, Samson LD, Hunter DJ. Polymorphisms in DNA double strand break repair genes and skin cancer risk. Cancer Res . 2004;64(9):3009-13. [abstract]

Han J, Hankinson SE, Colditz GA, Hunter DJ. Genetic variation in XRCC1, sun exposure, and risk of skin cancer. Br J Cancer. 2004;91(8):1604-9. [abstract]

Han J, Hankinson SE, Ranu H, De Vivo I, Hunter DJ. Polymorphisms in DNA double strand break repair genes and breast cancer risk in the Nurses’ Health Study. Carcinogenesis. 2004 Feb;25(2):189-95. Epub 2003 Oct 24. [abstract]

Han J, Colditz GA, Liu JS, Hunter DJ. Genetic variation in XPD, sun exposure, and risk of skin cancer. Cancer Epidemiol Biomarkers Prev. 2005;14(6):1539-44. [abstract]

Han, J, Tranah GJ, Hankinson SE, Samson LD, Hunter DJ. Polymorphisms in O6-methylguanine DNA methyltransferase and breast cancer risk. Pharmacogenet Genomics. 2006 Jul;16(7):469-474. [abstract]

Han J, Colditz GA, Hunter DJ. Lack of associations between selected variants of genes involved in cell cycle and apoptosis and skin cancer risk. Cancer Epidemiol Biomarkers Prev. 2006 Mar;15(3):592-3. No abstract available.

Han J, Cox DG, Colditz GA, Hunter DJ. The p53 codon 72 polymorphism, sunburns, and risk of skin cancer in US Caucasian women. Molecular Carcinogenesis. 2006; in press.

Han J, Kraft P, Colditz GA, Wong J, Hunter DJ. Melanocortin 1 receptor variants and skin cancer risk. Int J Cancer. 2006; in press.

Han J, Hankinson SE, De Vivo I. Polymorphisms in O6-methylguanine DNA methyltransferase and endometrial cancer risk. Carcinogenesis. 2006; in press.