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Xiang Gao, M.D., Ph.D.

Assistant Professor in Medicine
Harvard Medical School

Associate Epidemiologist
Brigham and Women's Hospital



xiang.gao@channing.harvard.edu


Research Interests

Dr. Gao's current research aims to investigate relationships between environmental/genetic factors and risk of neurological diseases, including Parkinson's disease (PD), restless legs syndrome (RLS), and other sleep disorders. Data from several large ongoing prospective cohorts have been used, including Nurses' Health Study, Health Professionals Follow-up Study, and Cancer Prevention Study II Nutrition Cohort. His research interests also include nutrition policy, cognitive function, dietary methodology, and international health.

Dr. Gao is the Principal Investigator of an NIH-funded R01 project entitled "Prospective Study of Restless Legs Syndrome" and serves on the Committee on Nutrition, Trauma, and the Brain, Institute of Medicine of the National Academies. Dr. Gao was a recipient of the Irwin H. Rosenberg Award from Jean Mayor USDA Human Nutrition Research Center on Aging at Tufts University in 2006 and the Wayne A. Hening Sleep Medicine Investigator Award from the American Academy of Neurology in 2011.


Selected Publications

Gao X, Chen H, Schwarzschild MA, Ascherio A. A prospective study of bowel movement frequency and Parkinson disease risk. Am J Epidemiol, 2011, in press.

Liu R, Gao X, Lu Y, Chen H. Meta-analysis on the relationship between Parkinson disease and melanoma. Neurology, 2011, in press.

Gao X, Chen H, Schwwarzschild MA, Ascherio A. Use of ibuprofen and risk of Parkinson disease. Neurology. 2011 Mar 8;76(10):863-9. Epub 2011 Mar 2. PMID: 21368281 [PubMed - in process]. [Abstract]

Gao X, Lyall K, Palacios N, Walters AS, Ascherio A. RLS in middle age women and attention deficit/hyperactivity disorder in their offspring. Sleep Med. 2011 Jan;12(1):89-91. PMID: 20810309 [PubMed - in process]. [Abstract]

Li F, Peng M, Jiang L, Sun Q, Zhang K, Lian F, Litonjua AA, Gao J, Gao X. Vitamin D deficiency is associated with decreased lung function in Chinese adults with asthma. Respiration. 2010 Dec 1. [Epub ahead of print]. PMID: 21124013 [PubMed - as supplied by publisher].

Bermudez OI, Gao X. Greater consumption of sweetened beverages and added sugars are associated with obesity among US young adults. Ann Nutr Metab. 2010;57(3-4):211-8. Epub 2010 Nov 19. PMID: 21088388 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Schwarzschild MA, O'Reilly EJ, Wang H, Ascherio A. Restless legs syndrome and parkinson's disease in men. Mov Disord. 2010 Nov 15;25(15):2654-7. PMID: 20737545 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Lai CQ, Scott T, Shen J, Cai T, Ordovas JM, Tucker KL. Urinary 8-hydroxy-2-deoxyguanosine and cognitive function in Puerto Rican adults. Am J Epidemiol. 2010 Aug 1;172(3):271-8. Epub 2010 Jul 9. PMID: 20621990 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Schwarzschild MA, O'Reilly EJ, Wang H, Ascherio A. Restless legs syndrome and erectile dysfunction. Sleep. 2010 Jan 1;33(1):75-9. PMID: 20120623 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Simon KC, Han J, Schwarzschild MA, Ascherio A. Family history of melanoma and Parkinson's disease risk. Neurology. 2009 Oct 20;73(16):1286-91. PMID: 19841380 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Schwarzschild MA, Wang H, Ascherio A. Obesity and restless legs syndrome in men and women. Neurology. 2009 Apr 7;72(14):1255-61. PMID: 19349606 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Scott T, Falcon LM, Wilde PE, Tucker KL. Food insecurity and cognitive function in Puerto Rican adults. Am J Clin Nutr. 2009 Apr;89(4):1197-203. Epub 2009 Feb 18. PMID: 19225117 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Simon KC, Han J, Schwarzschild MA, Ascherio A. Genetic determinants of hair color and Parkinson's disease. Ann Neurol. 2009 Jan;65(1):76-82. PMID: 19194882 [PubMed - indexed for MEDLINE]. [Abstract]

Logroscino G, Gao X, Chen H, Wing A, Ascherio A. Dietary iron intake and risk of Parkinson's disease. Am J Epidemiol. 2008 Dec 15;168(12):1381-8. Epub 2008 Oct 21. PMID: 18945687 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Chen H, Choi HK, Curhan G, Schwarzschild MA, Asherio A. Diet, urate, and Parkinson's disease risk in men. Am J Epidemiol. 2008 Apr 1;167(7):831-8. Epub 2008 Mar 7. PMID: 18326873 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Curhan G, Forman J, Asherio A, Choi HK. Vitamin C intake and serum uric acid concentration in men. J Rheumatol. 2008 Sep;35(9):1853-8. Epub 2008 May 1. PMID: 18464304 [PubMed - indexed for MEDLINE]. [Abstract]

Henkin S, Brugge D, Bermudez OI, Gao X. A case-control study of body mass index and asthma in Asian children. Ann Allergy Asthma Immunol. 2008 May;100(5):447-51. PMID: 18517076 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Chen H, Schwarzschild MA, Logroscino G, Ascherio A. Perceived imbalance and risk of Parkinson's disease. Mov Disord. 2008 Mar 15;23(4):613-6. PMID: 18181208 [PubMed - indexed for MEDLINE]. [Abstract]

Wang H, Chen H, Gao X, McGrath M, Deer D, De Vivo I, Schwarzschild MA, Ascherio A. Telomere length and risk of Parkinson's disease. Mov Disord. 2008 Jan 30;23(2):302-5. PMID: 18044760 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Chen H, Fung TT, Logroscino G, Schwarzschild MA, Hu FB, Ascherio A. Prospective study of dietary pattern and risk of Parkinson's disease. Am J Clin Nutr. 2007 Nov;86(5):1486-94. PMID: 17991663 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Chen H, Schwarzschild MA, Glasser DB, Logroscino G, Rimm EB, Ascherio A. Erectile function and risk of Parkinson's disease. Am J Epidemiol. 2007 Dec 15;166(12):1446-50. Epub 2007 Sep 17. PMID: 17875583 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Lu Q, Qiao N, Choi HK, Curhan G, Tucker KL, Ascherio A. Intake of added sugar and sugar-sweetened drink and serum uric acid concentration in US men and women. Hypertension. 2007 Aug;50(2):306-12. Epub 2007 Jun 25. PMID: 17592072 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Nelson ME, Tucker KL. Television viewing is associated with prevalence of metabolic syndrome in Hispanic elders. Diabetes Care. 2007 Mar;30(3):694-700. PMID: 17327343 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X. Model-letter Calligraphy and Weng Tonghe. Orientations. 38(3): 61. No abstract available.

Gao X, Martin A, Lin H, Bermudez OI, Tucker KL. alpha-Tocopherol intake and plasma concentration of Hispanic and non-Hispanic white elders is associated with dietary intake pattern. J Nutr. 2006 Oct;136(10):2574-9. PMID: 16988129 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Wilde PE, Lichtenstein AH, Tucker KL. Meeting adequate intake (AI) for dietary calcium without dairy foods in adolescents, aged 9-18 years. (National Health and Nutrition Examination Survey 2001-2002). J Am Diet Assoc. 2006 Nov;106(11):1759-65. PMID: 17081826 [PubMed - indexed for MEDLINE]. [Abstract] Related Editorial: Weaver CM. Back to basics: Have milk with meals. J Am Diet Assoc. 2006 Nov;106(11):1756-8. PMID: 17081825 [PubMed - indexed for MEDLINE].

Gao J, Shan G, Sun B, Thompson PJ, Gao X. Association between polymorphism of tumor necrosis factor alpha-308 and asthma: a meta-analysis. Thorax. 2006 Jun;61(6):466-71. Epub 2006 Mar 3. PMID: 16517578 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Wilde PE, Lichtenstein AH, Tucker KL. The 2005 USDA food guide pyramid is associated with more adequate nutrient intakes within energy constraints than the 1992 pyramid. J Nutr. 2006 May;136(5):1341-6. PMID: 16614427 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Wilde PE, Lichtenstein AH, Bermudez OI, Tucker KL. The maximal amount of dietary alpha-tocopherol intake in U.S. adults (NHANES 2001-2002). J Nutr. 2006 Apr;136(4):1021-6. PMID: 16549468 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, LaValley MP, Tucker KL. Prospective studies of diary product and calcium intakes and prostate cancer risk: A meta-analysis. J Natl Cancer Inst. 2005 Dec 7;97(23):1768-77. PMID: 16333032 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Wilde PE, Maras JE, Bermudez OI, Tucker KL. The maximal amount of alpha-tocopherol intake from foods alone in U.S. adults (1994-96 CSFII): An analysis by linear programming. Ann N Y Acad Sci. 2004 Dec;1031:385-6. PMID: 15753176 [PubMed - indexed for MEDLINE]. No abstract available.

Gao X, Bermudez OI, Tucker KL. Plasma C-reactive protein and homocysteine concentrations are related to frequent fruit and vegetable intake in Hispanic and non-Hispanic white elders. J Nutr. 2004 Apr;134(4):913-8. PMID: 15051846 [PubMed - indexed for MEDLINE]. [Abstract]

Gao X, Yao M, McCrory MA, Ma G, Li Y, Roberts SB, Tucker KL. Dietary pattern is associated with homocysteine and B vitamin status in an urban Chinese population. J Nutr. 2003 Nov;133(11):3636-42. PMID: 14608087 [PubMed - indexed for MEDLINE]. [Abstract]

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